The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery …
Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Volume One: Types and Triggers discusses, in detail, the recent trends in designing biodegradable and biocompatible single-responsive polymers and nanoparticles for safe drug delivery. Focusing on the most advanced materials and technologies, evaluation methods, and advanced synthesis techniques stimuli-responsive
The traditional design of stimuli-responsive NMs is based on the incorporation of drug molecules into the nanocarrier, which is prepared from pH-sensitive building blocks. However, under acidic conditions, drug delivery systems tend to demonstrate burst drug release instead of extended-release. Smart polymers. Stimuli-responsive polymers. Poly (N-isopoprylacrilamide).
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Adv Drug Deliv Rev. 2013 Nov;65(13-14):1699-715. doi: 10.1016/j.addr.2013.04.011. Epub 2013 Apr 20. Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor.
The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications.
Implementation of such devices requires the use of biocompatible materials that are susceptible to a specifi … Pris: 1619 kr. Inbunden, 2018. Skickas inom 5-8 vardagar. Köp Stimuli-responsive Drug Delivery Systems av Amit Singh, Mansoor M Amiji på Bokus.com.
Title: Stimuli-Responsive Molecularly Imprinted Polymers for Drug Delivery: A Review VOLUME: 5 ISSUE: 2 Author(s):Francesco Puoci, Francesca Iemma and Nevio Picci Affiliation:Dipartimento di Scienze Farmaceutiche, Universita della Calabria - Edificio Polifunzionale, Arcavacata di Rende (CS) 87036, Italy. Keywords:Molecularly imprinted polymers, stimuli-responsive systems, intelligent drug delivery
These "smart" materials can act rapidly at the site of interest while avoiding biological barriers, toxicity, and other potential detrimental effects.
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become possible. Implementation of such devices requires the use of biocompatible materials that are susceptible to a specifi …
2021-01-01 · Designing different stimuli-responsive drug delivery based on CD. At the end of the 20th century, heat-sensitive liposomes were used for local drug release to treat diseases, triggering the concept of stimuli-responsive drug delivery system ( Yatvin, Weinstein, Dennis, & Blumenthal, 1978 ). Pris: 1619 kr. Inbunden, 2018. Skickas inom 5-8 vardagar. Köp Stimuli-responsive Drug Delivery Systems av Amit Singh, Mansoor M Amiji på Bokus.com. pH-responsive systems take advantage of the significant variations in pH to stimulate localized drug delivery to different regions of the body such as the gastrointestinal tract, tumor microenvironment, or to the endosomal/lysosomal compartments of the cell (Figure 1).
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Stimuli-responsive materials, which exhibit changes in one or more properties in response to an external trigger, have gained interest due to their tunability and versatility. Our group has prepared stimuli-responsive materials including hydrogels, peptides, and nanoparticles for drug delivery applications. Intrinsic stimuli‐responsive nanocarriers have gained significant interest in the antibacterial research field. In this review, we discuss the potential of these nanocarriers for improved antibacterial drug delivery and highlight further research required to optimize their potential. Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery.
Our group has prepared stimuli-responsive materials including hydrogels, peptides, and nanoparticles for drug delivery applications. Intrinsic stimuli‐responsive nanocarriers have gained significant interest in the antibacterial research field. In this review, we discuss the potential of these nanocarriers for improved antibacterial drug delivery and highlight further research required to optimize their potential. Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery.
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Once a stimuli-responsive drug delivery system is subtly designed, loading the drug in the carrier could ideally achieve the on-demand release of the drug according to different environment of the disease/physiology or the dynamic process of the organism itself.
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become possible.